Mediana is a luxury suburb of the ancient city of Naisuss (present-day Niš), which was built in the late 3rd and early 4th centuries during the reign of Roman Emperor Constantine the Great and his successors. Today, Mediana is one of the most important archeological parks in Serbia, where on the surface of 40 hectares one can see the remains of a magnificent villa with peristyle, the remains of two early Christian churches, parts of a granary, military barracks and water towers. Visitors can also see more than 1,000 square feet of floor mosaics, which evoke part of the splendor of this unique Imperial residence. Central to the Mediana is a villa with peristyle, the most luxurious residential building. The villa was probably built at the behest of Roman Emperor Constantine the Great, in order to create for himself, his family members and numerous high imperial servants the conditions for a visit during a visit to Naisus.

The entire complex of the villa was enclosed by a high wall, occupying an area of 4.7 hectares, and one seventh of the total area was paved with mosaics. Most mosaics had decorative, geometric motifs, and some of them can still be seen on the Median today. The two best-preserved mosaics that attract particular attention are mosaics with figural representations of the mythological, word-deity Fluvius and the head of Medusa.